The ADAMTS10 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ADAMTS10. This antibody recognizes Human, Mouse, and Rat antigen. The ADAMTS10 Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome